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Article

Molecular population genetics of an electrophoretically monomorphic protein in the alcohol dehydrogenase region of Drosophila pseudoobscura.

Genetics - 1 Sept 1992

Schaeffer S W, Miller E L

Abstract excerpt

Nucleotide sequence data from the alcohol dehydrogenase (Adh) region of 18 isochromosomal strains of Drosophila pseudoobscura were used to determine whether the lack of amino acid polymorphism in ADH results from a low neutral mutation rate or a recent directional selection event. We estimated the neutral mutation parameter, 4Nmu, in synonymous sites for 17 subregions of Adh. The nucleotide diversity data were...

Topics

Alcohol Dehydrogenase
Alleles
Amino Acid Sequence
Animals
Base Sequence
Chromosome Mapping
DNA
Drosophila
Electrophoresis
Genetic Variation
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Recombination, Genetic

Selection, Genetic

Sequence Homology, Nucleic Acid

Species Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 1398051
DOI: 10.1093/genetics/132.1.163
PMCID: PMC1205114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1398051-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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