Article
Mutation of the core region of HBV-DNA and submassive hepatic necrosis in patients with anti-HBe-positive chronic hepatitis B.
Journal of gastroenterology and hepatology - 1 Jan 2000
Nonaka T, Onji M, Horiike N, Ohta Y
Abstract excerpt
Three patients with submassive hepatic necrosis developed acute liver failure during the severe reactivation of chronic hepatitis B. The activity of hepatitis B virus (HBV) DNA polymerase increased in all three patients immediately before the onset of hepatic failure. Liver biopsy specimens obtai...
Topics
- Adult
- Amino Acid Sequence
- Base Sequence
- DNA, Viral
- Female
- Hepatitis B
- Hepatitis B Antibodies
- Hepatitis, Chronic
- Humans
- Liver
- Male
- Middle Aged
- Molecular Sequence Data