Article
The beta-thalassaemia mutations in the population of Cyprus.
British journal of haematology - 1 Aug 1992
Baysal E, Indrak K, Bozkurt G, Berkalp A, Aritkan E, Old J M, Ioannou P, Angastiniotis M, Droushiotou A, Yüregir G T
Abstract excerpt
We have identified the beta-thalassaemia alleles in nearly all known Turkish Cypriot beta-thalassaemia homozygotes and in over 700 Greek Cypriot beta-thalassaemia heterozygotes living on the island of Cyprus. The data confirmed earlier observations that the IVS-I-100 (G-->A) mutation is present for about 74-80%, while three other alleles [IVS-II-745 (C-->G), IVS-I-6 (T-->C), IVS-I-1 (G-->A)] occur at frequencies...
Topics
- Alleles
- Cyprus
- Greece
- Humans
- Mutation
- Thalassemia
- Turkey