Combined 10pter-->p11 and 18pter-->q11 trisomy in a 7-year-old child.

Article

Combined 10pter-->p11 and 18pter-->q11 trisomy in a 7-year-old child.

Genetic counseling (Geneva, Switzerland) - 1 Jan 1992

Lapière J C, Verloes A, Herens C, Delfortrie J, Van Maldergem L, Gillerot Y, Koulischer L

Abstract excerpt

We report a severely mentally retarded, dysmorphic girl aged 7 years with a 47,XX, +der(18), t(10;18)(p11.2;q11.2)mat. The phenotype of our patient is compared with 6 cases of trisomy 10p and 10 cases of trisomy 18q- from the literature. The short trisomic segment 10pter-10p11 appears to affect m...

Topics

Abnormalities, Multiple
Child
Chromosomes, Human, Pair 10
Chromosomes, Human, Pair 18
Female
Humans
Intellectual Disability
Karyotyping
Phenotype
Trisomy

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