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Article

T lymphocyte adhesion to fibronectin (FN): a possible mechanism for T cell accumulation in the rheumatoid joint.

Clinical and experimental immunology - 1 Sept 1992

Rodriguez R M, Pitzalis C, Kingsley G H, Henderson E, Humphries M J, Panayi G S

Abstract excerpt

The accumulation of T cells within the joint is responsible for the perpetuation of synovitis. This process is partly regulated by selective binding to endothelium. However, adhesion to extra-cellular matrix proteins, like FN, may also be important. FN binding is mediated by certain members of the VLA (beta 1 integrin) family of proteins. To investigate the role of Tc-FN interactions in synovitis the binding of...

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Identifiers

PMID: 1387596
DOI: 10.1111/j.1365-2249.1992.tb06977.x
PMCID: PMC1554473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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