Article
A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping and DNA sequence data. III. Cladogram estimation.
Genetics - 1 Oct 1992
Templeton A R, Crandall K A, Sing C F
Abstract excerpt
We previously developed a cladistic approach to identify subsets of haplotypes defined by restriction endonuclease mapping or DNA sequencing that are associated with significant phenotypic deviations. Our approach was limited to segments of DNA in which little recombination occurs. In such cases, a cladogram can be constructed from the restriction site or sequence data that represents the evolutionary steps that...
Topics
- Alcohol Dehydrogenase
- Algorithms
- Amylases
- Animals
- Carboxylesterase
- Carboxylic Ester Hydrolases
- Drosophila melanogaster
- Genetic Techniques
- Haplotypes
- Mutation
- Phenotype
