Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The amino terminus of human cytomegalovirus glycoprotein B contains epitopes that vary among strains.

The Journal of general virology - 1 Apr 1992

Basgoz N, Qadri I, Navarro D, Sears A, Lennette E, Youngblom J, Pereira L

Abstract excerpt

We mapped three antigenic domains of continuous epitopes on human cytomegalovirus (CMV) glycoprotein B (gB) by reacting a panel of independently derived monoclonal antibodies with deletion mutants expressed transiently in COS-1 cells. One of these antigenic domains, DC2, maps in the last 75 amino acids of the carboxy terminus. These epitopes are conserved in strains Towne and AD169, as well as in 19 clinical CMV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Antibodies, Monoclonal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to DNA Mutational Analysis

Share to Epitopes

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Protein Conformation

Source

Identifiers

PMID: 1378884
DOI: 10.1099/0022-1317-73-4-983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The amino terminus of human cytomegalovirus glycoprotein B contains epitopes that vary among strains.PMID 1378884Read ↗

Analysis of interstrain variation in cytomegalovirus glycoprotein B sequences encoding neutralization-related epitopes.Semantic proximity Read ↗

Sequence variation of the amino-terminal antigenic domains of glycoprotein B of human cytomegalovirus strains isolated from Chinese patients.Semantic proximity Read ↗

Molecular epidemiology of envelope glycoprotein H of human cytomegalovirus.Semantic proximity Read ↗

Crystal Structure of the Human Cytomegalovirus Glycoprotein BSemantic proximity Read ↗

Site directed mutagenesis of the carboxyl terminus of human cytomegalovirus glycoprotein B leads to attenuation of viral growth in cell culture.Semantic proximity Read ↗

The cytomegalovirus gB/MF59 vaccine candidate induces antibodies against an antigenic domain controlling cell-to-cell spreadSemantic proximity Read ↗

Vaccination with a disabled infectious single cycle cytomegalovirus vaccine elicits a distinct glycoprotein B-specific monoclonal antibody repertoire compared to that of naturally-infected individualsSemantic proximity Read ↗

A continuous sequence of more than 70 amino acids is essential for antibody binding to the dominant antigenic site of glycoprotein gp58 of human cytomegalovirusSemantic proximity Read ↗

Distribution of linear antigenic sites on glycoprotein gp55 of human cytomegalovirusSemantic proximity Read ↗

Sequence variation within neutralizing epitopes of the envelope glycoprotein B of human cytomegalovirus: comparison of isolates from renal transplant recipients and AIDS patients.Semantic proximity Read ↗

HCMV Envelope Glycoprotein Diversity DemystifiedSemantic proximity Read ↗

A Vaccine Based on the Rhesus Cytomegalovirus UL128 Complex Induces Broadly Neutralizing Antibodies in Rhesus MacaquesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.