Article
The amino terminus of human cytomegalovirus glycoprotein B contains epitopes that vary among strains.
The Journal of general virology - 1 Apr 1992
Basgoz N, Qadri I, Navarro D, Sears A, Lennette E, Youngblom J, Pereira L
Abstract excerpt
We mapped three antigenic domains of continuous epitopes on human cytomegalovirus (CMV) glycoprotein B (gB) by reacting a panel of independently derived monoclonal antibodies with deletion mutants expressed transiently in COS-1 cells. One of these antigenic domains, DC2, maps in the last 75 amino...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antigens, Viral
- Cell Line, Transformed
- Chromosome Mapping
- Cytomegalovirus
- DNA Mutational Analysis
- Epitopes
- Genetic Variation
- Humans
- Molecular Sequence Data
- Peptide Fragments
- Protein Conformation
- Viral Envelope Proteins