Article
Antigenic diversity of human parainfluenza virus type 1 isolates and their immunological relationship with Sendai virus revealed by using monoclonal antibodies.
The Journal of general virology - 1 Apr 1992
Komada H, Kusagawa S, Orvell C, Tsurudome M, Nishio M, Bando H, Kawano M, Matsumura H, Norrby E, Ito Y
Abstract excerpt
Fifty-six monoclonal antibodies (MAbs) directed against human parainfluenza virus type 1 (hPIV-1) were prepared in order to identify the structural proteins of hPIV-1, to examine the immunological relationship between hPIV-1 and Sendai virus (SV), and to determine the antigenic diversity of clinical isolates of hPIV-1. In addition, 41 MAbs characterized previously and directed against SV were used for...
Topics
- Antibodies, Monoclonal
- Cross Reactions
- Epitopes
- Genes, Viral
- Genetic Variation
- Humans
- Neutralization Tests
- Parainfluenza Virus 1, Human
- Paramyxoviridae Infections
- Phosphoproteins
