Article
Analysis of the spectrum of mutations induced by the rad3-102 mutator allele of yeast.
Mutation research - 1 May 1992
Montelone B A, Gilbertson L A, Nassar R, Giroux C, Malone R E
Abstract excerpt
The product of the RAD3 gene of Saccharomyces cerevisiae is required for mitotic cell viability and excision repair of UV-induced pyrimidine dimers. Certain rad3 mutant alleles (originally called rem1) increase the rates of both spontaneous mitotic recombination and mutation. The increase in muta...
Topics
- Adenosine Triphosphatases
- Alleles
- Base Sequence
- DNA Helicases
- DNA Repair
- DNA Replication
- Genes, Fungal
- Genes, Suppressor
- Molecular Sequence Data
- Mutation
- Plasmids
- Saccharomyces cerevisiae
