Article
Neonatal, urogenital isolates of biotype 4 nontypeable Haemophilus influenzae express a variant P6 outer membrane protein molecule.
Infection and immunity - 1 May 1992
Murphy T F, Kirkham C, Sikkema D J
Abstract excerpt
The P6 outer membrane protein is a highly conserved molecule which is present on the surface of all strains of Haemophilus influenzae. Sixty strains of nontypeable H. influenzae which caused invasive disease or colonized the female urogenital tract were studied with monoclonal antibodies 7F3 and 4G4, which recognize different surface-exposed epitopes on the P6 molecule. All 60 strains expressed the epitope...
Topics
- Antibodies, Monoclonal
- Bacterial Outer Membrane Proteins
- Base Sequence
- Enzyme-Linked Immunosorbent Assay
- Epitopes
- Haemophilus influenzae
- Humans
- Infant, Newborn
- Molecular Sequence Data
- Phenotype
- Recombinant Proteins
