Selective gene mutation in MEL cells.

doi:10.1016/0027-5107(92)90048-7

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Article

Selective gene mutation in MEL cells.

Mutation research - 1 Feb 1992

Foresti M, Gaudio L, Geraci G

Abstract excerpt

MEL cells, undergoing erythroid differentiation and parasynchronized by dimethyl sulfoxide (DMSO) induction, were irradiated with a 3-s pulse of UV light at sublethal dose. A large number of clones deficient in different gene functions are found in the progeny of the treated cells, if the pulse i...

Topics

Cell Differentiation
Centrifugation, Density Gradient
DNA Damage
Dimethyl Sulfoxide
Erythrocytes
Glucosephosphate Dehydrogenase
Hemoglobins
Kinetics
Mutation
Phosphogluconate Dehydrogenase
S Phase
Tumor Cells, Cultured
Ultraviolet Rays

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