Article
Association between novel GM-CSF gene polymorphisms and the frequency and severity of atopic dermatitis.
The Journal of allergy and clinical immunology - 1 Sept 2003
Rafatpanah Houshang, Bennett Elizabeth, Pravica Vera, McCoy Melanie J, David Timothy J, Hutchinson Ian V, Arkwright Peter D
Abstract excerpt
BACKGROUND: Genetic factors are known to be important in determining an individual's predisposition to atopic dermatitis. The specific genes that are clinically important in this process are still largely unknown. OBJECTIVE: Because dendritic cells initiate immune responses and thus are critical to the priming of an individual to potential allergens, we hypothesized that genetic factors controlling the activity...
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