Article
Increased number of alveolar macrophages expressing adhesion molecules of the leukocyte adhesion molecule family in smoking subjects. Association with cell-binding ability and superoxide anion production.
The American review of respiratory disease - 1 Nov 1992
Schaberg T, Lauer C, Lode H, Fischer J, Haller H
Abstract excerpt
This study was designed to investigate whether the expression and functional properties of leukocyte adhesion molecules (LeuCAM; CD11/CD18) are altered in human alveolar macrophages (AM) from smokers. Cells were obtained from 38 smokers (S) and 27 nonsmokers (NS) by bronchoalveolar lavage (BAL). Expression of LeuCAM on freshly isolated cells was studied using a sensitive peroxidase-antiperoxidase method with...
Topics
- Adult
- Aged
- Antigens, CD
- Bronchoalveolar Lavage Fluid
- CD11 Antigens
- CD18 Antigens
- Cell Adhesion
- Endothelium, Vascular
- Evaluation Studies as Topic
- Female