Article
Gonad formation and development requires the abd-A domain of the bithorax complex in Drosophila melanogaster.
Development (Cambridge, England) - 1 Jun 1992
Cumberledge S, Szabad J, Sakonju S
Abstract excerpt
The abdominal-A (abd-A) gene, a member of the bithorax complex, is required for the correct identity of parasegments (PS) 7 through 13. Mutations in iab-4, one of the cis-regulatory regions of abd-A, transform epidermal structures of PS 9 and also cause loss of gonads in adult flies. Here, we des...
Topics
- Animals
- Chimera
- Drosophila melanogaster
- Female
- Gene Expression
- Genes, Homeobox
- Immunohistochemistry
- Male
- Mesoderm
- Mutation
- Nuclear Transfer Techniques
- Ovary
- Testis
