Article
Hormonal profiles in Italian late-onset adrenal hyperplasia correlate with HLA class III polymorphisms.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jun 1992
Balsamo A, Revelli A, Borelli I, Amoroso A, Cenderelli G, De Sanso G, Mazzola G, Curtoni E S, Zoppetti G, Massobrio M
Abstract excerpt
To investigate the genetic polymorphisms of the HLA region in late-onset adrenal hyperplasia, 13 Italian patients affected by the disease were analyzed for: (1) HLA-A and -B typing; (2) restriction fragment length polymorphism (RFLP) of DR beta, DQ beta, DQ alpha, 21-hydroxylase A and B genes; (3...
Topics
- 17-alpha-Hydroxyprogesterone
- Adolescent
- Adrenal Hyperplasia, Congenital
- Adrenocorticotropic Hormone
- Adult
- Complement C4b
- Complement System Proteins
- Female
- Gonadal Steroid Hormones
- HLA Antigens
- HLA-B Antigens
- HLA-B14 Antigen
- HLA-DQ Antigens