Article
Combination of GM-CSF and cytosine in myelodysplasia results in improved neutrophil function.
Acta haematologica - 1 Jan 1992
Galvani D W, Dang Y, Watson F, Pumford D, Galazka A, Weiner J, Davies J M, Cawley J C
Abstract excerpt
Granulocyte-macrophage colony-stimulating factor (GM-CSF) was given concurrently with low-dose cytosine arabinoside for 3 weeks to patients with myelodysplasia. Neutrophil activation as evidenced by increased chemiluminescence and reduced surface expression of CD16 was consistently seen during th...
Topics
- Antigens, CD
- Antigens, Differentiation
- Blood Cell Count
- Bone Marrow
- CD11 Antigens
- CD18 Antigens
- Cytosine
- Drug Evaluation
- Drug Therapy, Combination
- Granulocyte-Macrophage Colony-Stimulating Factor
- Humans
- Myelodysplastic Syndromes
- Neutrophils
- Phenotype
- Receptors, Fc
- Receptors, IgG
- Recombinant Proteins