Structure and identity of a late-replicating and transcriptionally active gene.

Abstract excerpt

Eukaryotic genes are usually replicated early during S-phase in the cell lineages in which they are expressed. Using partially characterized cDNA probes, we recently established two exceptions to this rule in the slime mold Physarum polycephalum. In this paper, we analyzed the structure and the identity of one of these two genes. By genomic cloning and Southern analysis we demonstrate that it is a single-copy...

Topics

• Alleles
• Amino Acid Sequence
• Animals
• Base Sequence
• DNA Replication
• Genes, Fungal
• Molecular Sequence Data
• Physarum polycephalum
• Polymorphism, Restriction Fragment Length
• RNA, Messenger
• S Phase