Article
Molecular strategies in genetic diagnosis of transthyretin-related hereditary amyloidosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 1992
Ferlini A, Fini S, Salvi F, Patrosso M C, Vezzoni P, Forabosco A
Abstract excerpt
Transthyretin-related hereditary (TTR) amyloidoses represent a clinically heterogeneous group of diseases associated with various point mutations of the TTR gene. We propose a molecular strategy for the diagnosis of this group of disorders.
Topics
- Amyloidosis
- Base Sequence
- Cloning, Molecular
- Humans
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Prealbumin