The lipoprotein lipase Gly188----Glu mutation in South Africans of Indian descent: evidence suggesting common origins and an increased frequency.

doi:10.1136/jmg.29.2.119

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Article

The lipoprotein lipase Gly188----Glu mutation in South Africans of Indian descent: evidence suggesting common origins and an increased frequency.

Journal of medical genetics - 1 Feb 1992

Henderson H E, Hassan F, Berger G M, Hayden M R

Abstract excerpt

Lipoprotein lipase (LPL) plays a crucial role in the hydrolysis of the triglyceride core of circulating chylomicrons and very low density lipoproteins (VLDL) and also has a major effect on the levels and lipid composition of high density lipoproteins (HDL). LPL deficiency is inherited as an autos...

Topics

Base Sequence
DNA
Female
Gene Frequency
Glutamine
Glycine
Humans
India
Lipoprotein Lipase
Male
Molecular Sequence Data
Mutation
Pedigree
Polymorphism, Restriction Fragment Length
South Africa

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