Familial association of autoimmune thrombocytopenia and hyperthyroidism.

Abstract excerpt

An association between thrombocytopenia and thyrotoxicosis in a single individual is well documented, and the theories for this event include a common immunologic cause or a thyrotoxic-induced decrease in platelet survival. We report the first description of the coexistence of autoimmune thrombocytopenic purpura (AITP) and Graves' disease in several members of the same family, in which four females were...

Topics

• Adult
• Autoantibodies
• Female
• Genotype
• Graves Disease
• HLA Antigens
• Haplotypes
• Humans
• Immunoglobulins, Thyroid-Stimulating
• Male
• Middle Aged
• Phenotype