Article
Immune thrombocytopenia with antiphospholipid antibodies in monozygotic twins.
Platelets - 1 Jan 2012
Ninfea Jose Ignacio Ruades, Basquiera Ana Lisa, Tabares Aldo Hugo, Mas Luciana, Alvarellos Teresita, Garcia Juan Jose
Abstract excerpt
We describe monozygotic twins with immune thrombocytopenia (ITP) associated to antiphospholipid antibodies with a dissimilar clinical expression. The first patient was diagnosed to have ITP at 63 years old and was treated with corticosteroids. She presented ulterior exacerbations of thrombocytopenia requiring intravenous immunoglobulin and subsequent treatment with rituximab. She ultimately had a favorable...
Topics
- Antibodies, Antiphospholipid
- Antiphospholipid Syndrome
- Diseases in Twins
- Female
- Genes, MHC Class I
- Genes, MHC Class II
- Genotype
- Humans
- Middle Aged
- Purpura, Thrombocytopenic, Idiopathic
- Twins, Monozygotic