Article
Effects of acyclovir, oxetanocin-G, and carbocyclic oxetanocin-G in combinations on the replications of herpes simplex virus type 1 and type 2 in Vero cells.
The Tohoku journal of experimental medicine - 1 May 1992
Saijo M, Suzutani T, Yoshida I
Abstract excerpt
9-(2-hydroxyethoxymethyl)guanine (acyclovir, ACV) and novel nucleosides, 9-(2-deoxy-2-hydroxymethyl-beta-D-erythro-oxetanocyl)guanine (oxetanocin-G, OXT-G) and (+)-9-[(1R, 2R, 3S)-2, 3-bis(hydroxymethyl)cyclobutyl]guanine (carbocyclic oxetanocin-G, carbocyclic OXT-G) possessed substantial antivir...
Topics
- Acyclovir
- Animals
- Antiviral Agents
- Cell Survival
- Drug Interactions
- Guanine
- Molecular Structure
- Mutation
- Phosphorylation
- Simplexvirus
- Thymidine
- Vero Cells
- Viral Plaque Assay
- Virus Replication