Article
Molecular diversity in the adenylylcyclase family. Evidence for eight forms of the enzyme and cloning of type VI.
The Journal of biological chemistry - 5 Dec 1992
Krupinski J, Lehman T C, Frankenfield C D, Zwaagstra J C, Watson P A
Abstract excerpt
The conservation of amino acid sequence among types I-IV adenylylcyclase has made it possible to apply the polymerase chain reaction to examine the extent of the molecular diversity within this family of enzymes. cDNA templates from rat heart, liver, kidney, guinea pig brain and testes, and mouse skeletal muscle were amplified with primers specific to adenylylcyclase sequences. Evidence was obtained for a total...
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