Article
The colorectal cancer gene hunt: current findings.
Hospital practice (Office ed.) - 15 Nov 1992
Kinzler K W, Vogelstein B
Abstract excerpt
Identification of four genes, each with its own clinical significance, promises probes for early diagnosis of colorectal cancer in the near future. It also suggests possibilities for new forms of chemotherapy to offset the effects of mutated or lost genes. Given the "moving target" of metastasis,...
Topics
- Adenomatous Polyposis Coli
- Antineoplastic Agents
- Colorectal Neoplasms
- Genes, APC
- Genes, p53
- Humans
- Models, Genetic
- Mutation