Article
A role for GRIP domain proteins and/or their ligands in structure and function of the trans Golgi network.
Journal of cell science - 1 Nov 2003
Yoshino Atsuko, Bieler Bert M, Harper Dawn C, Cowan David A, Sutterwala Shaheen, Gay Denise M, Cole Nelson B, McCaffery J Michael, Marks Michael S
Abstract excerpt
tGolgin-1 (golgin-245, trans golgi p230) and golgin-97 are members of a family of peripheral membrane proteins of unknown function that localize to the trans Golgi network (TGN) through a conserved C-terminal GRIP domain. We have probed for GRIP protein function by assessing the consequences of overexpressing isolated GRIP domains. By semi-quantitative immunofluorescence microscopy we found that high level...
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