Article
Molecular basis of insulin resistance.
Hormone research - 1 Jan 1992
Clauser E, Leconte I, Auzan C
Abstract excerpt
The recent application of recombinant DNA technology to clinical investigation now allows the identification of the molecular alterations responsible for insulin resistance. In this review, the recent knowledge concerning these investigations is reported. Genetic mutations of the insulin gene as the source of insulin resistance have been reported for a long time. More recently a series of mutations of the insulin...
Topics
- Glucose Transporter Type 4
- Humans
- Insulin
- Insulin Resistance
- Monosaccharide Transport Proteins
- Muscle Proteins
- Mutation
- Receptor, Insulin
