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Article

Beta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion.

Oncogene - 11 Sept 2003

Usami Noriyasu, Sekido Yoshitaka, Maeda Osamu, Yamamoto Kazuhito, Minna John D, Hasegawa Yoshinori, Yoshioka Hiromu, Imaizumi Munehisa, Ueda Yuichi, Takahashi Masahide, Shimokata Kaoru

Abstract excerpt

We have found that a malignant mesothelioma cell line, NCI-H28, had a chromosome 3p21.3 homozygous deletion containing the beta-catenin gene (CTNNB1), which suggested that the deletion of beta-catenin might have a growth advantage in the development of this tumor. To determine whether beta-cateni...

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Source

Identifiers

PMID: 12970740
DOI: 10.1038/sj.onc.1206533

Genes

CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12970740-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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