Multiple Corticosteroid Receptors in a Teleost Fish: Distinct Sequences, Expression Patterns, and Transcriptional Activities

Abstract excerpt

Corticosteroid hormones, including the mineralocorticoids and the glucocorticoids, regulate diverse physiological functions in vertebrates. These hormones act through two classes of corticosteroid receptors (CR) that are ligand-dependent transcription factors: type I or mineralocorticoid receptor (MR) and type II or glucocorticoid receptor (GR). There is substantial overlap in the binding of these two receptor...