Article
Interferon-alpha (IFN alpha) daily dose versus IFN alpha plus ribavirin for treatment-naive chronic hepatitis c patients infected by genotype 1b.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy - 1 Jan 2003
Scotto Gaetano, Campanozzi Fausto, D'Adduzio Antonio, Grimaldi Maria, Fazio Vincenzina
Abstract excerpt
INTRODUCTION: Infection with hepatitis C virus genotype 1b (HCV1b) is known to be a predictive factor of poor response to both interferon-alpha (IFN alpha) alone and IFN alpha plus ribavirin combination therapy.STUDY DESIGN, PATIENTS AND METHODS: This randomised study evaluated the efficacy and safety of daily IFN alpha administration versus the combination of IFN alpha plus ribavirin in treatment-naive patients...
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