Article
Daily or three times a week interferon alfa-2b in combination with ribavirin or interferon alone for the treatment of patients with chronic hepatitis C.
Journal of hepatology - 1 May 2002
de Lédinghen Victor, Trimoulet Pascale, Winnock Maria, Foucher Juliette, Bourlière Marc, Desmorat Hervé, Canva Valérie, Capron Dominique, Lévy Stéphane, Mion François, Mannant Paul-Régis, Chêne Geneviève, Fleury Hervé, Couzigou Patrice, Bernard Pierre-Henri
Abstract excerpt
BACKGROUND/AIMS: Data on hepatitis C virus (HCV) viral dynamics and on the effect of interferon in blocking virion production have suggested a rationale for daily administration of interferon in patients with chronic hepatitis C infection. We compared the efficacy and safety of daily interferon alfa-2b in combination with ribavirin with those of interferon alfa-2b three times a week alone or in combination with...
Topics
- Adult
- Alanine Transaminase
- Antiviral Agents
- Biopsy
- Drug Therapy, Combination
- Female
- Follow-Up Studies
- Genotype
- Hepacivirus