Article
Tyrosine Phosphorylation of HSP-90 During Mammalian Sperm Capacitation1
1 Dec 2003
Abstract excerpt
The process of sperm capacitation is correlated with activation of a signal transduction pathway leading to protein tyrosine phosphorylation. Whereas phosphotyrosine expression is an essential prerequisite for fertilization, the proteins that are phosphorylated during capacitation have not yet been identified. In the present study, we observed that a major target of this signaling pathway is the molecular...
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