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[Antigenic specificity of Vibrio cholerae O139 nitrosoguanidine mutants].

Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000

Lobanov V V, Shestialtynoba I S, Agafonova V V, Sukhar' V V, Mazrukho B L, Aronova N A

Abstract excerpt

The action of nitrosoguanidine (NG) on the culture of V. cholerae O139 P-16064 resulted in the appearance of mutant 16064 NG6, not agglutinating with commercial diagnostic serum O139. Its incapacity of agglutination was due to the sorption of the specific serum with strains V. cholerae O22 and R-variant RCA-385, which caused the loss of antibodies to common determinants. Experiments with the sorption of immune...

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PMID: 12886640

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