Article
Differential expression of neuropilin-1 in malignant and benign prostatic stromal tissue.
Oncology reports - 1 Jan 2000
Vanveldhuizen Peter J, Zulfiqar Muhammad, Banerjee Snigdha, Cherian Rachel, Saxena Neela K, Rabe Amy, Thrasher J Brantley, Banerjee Sushanta K
Abstract excerpt
Neuropilin-1 (NRP-1), a co-receptor for VEGF165, is overexpressed in various prostate cancer cell lines and in advanced prostate tumors. However, distribution of the NRP-1 in prostate tumors has not yet been evaluated. Using immunohistochemical analysis, we evaluated 21 archival prostate tumors and 5 benign glands for the expression of NRP-1. In addition, we utilized a quantitative RT-PCR method to examine mRNA...
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