The quest for the function of simple epithelial keratins.

Abstract excerpt

Simple epithelial keratins K8 and K18 are components of the intracellular cytoskeleton in the cells of the single-layered sheet tissues inside the body. As members of the intermediate filament family of proteins, their function has been a matter for debate since they were first discovered. Whilst there is an indisputable case for a structural cell-reinforcing function for keratins in the mutilayered squamous...

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• Apoptosis
• Biological Evolution
• Epithelium
• Gene Expression
• Keratins
• Models, Biological