Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical heterogeneity in chronic myeloid leukaemia reflecting biological diversity in normal persons.

British journal of haematology - 1 Aug 2003

Gordon Myrtle Y, Marley Stephen B, Apperley Jane F, Marin David, Kaeda Jaspal, Szydlo Richard, Goldman John M

Abstract excerpt

The molecular basis of chronic myeloid leukaemia (CML) is well defined and highly consistent, yet prognosis varies considerably. This could reflect the biological diversity occurring in normal populations. We used a colony replating assay to measure the proliferative capacity of progenitor cells from 211 CML patients and 86 normal persons. Results were expressed as the frequency distributions of the proliferation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Benzamides
Share to Fusion Proteins, bcr-abl

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoietic Stem Cells

Share to Imatinib Mesylate

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Piperazines

Share to Protein-Tyrosine Kinases

Share to Pyrimidines

Source

Identifiers

PMID: 12877669
DOI: 10.1046/j.1365-2141.2003.04451.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Clinical heterogeneity in chronic myeloid leukaemia reflecting biological diversity in normal persons.PMID 12877669Read ↗

Differences in proliferative capacity of primary human acute myelogenous leukaemia cells are associated with altered gene expression profiles and can be used for subclassification of patients.Semantic proximity Read ↗

Genotypic and functional diversity of phenotypically defined primitive hematopoietic cells in patients with chronic myeloid leukemia.Semantic proximity Read ↗

Phenotypic heterogeneity of primitive leukemic hematopoietic cells in patients with chronic myeloid leukemia.Semantic proximity Read ↗

Characterization of primitive subpopulations of normal and leukemic cells present in the blood of patients with newly diagnosed as well as established chronic myeloid leukemiaSemantic proximity Read ↗

Autonomous Proliferation of Leukemic Cells in Vitro as a Determinant of Prognosis in Adult Acute Myeloid LeukemiaSemantic proximity Read ↗

Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level.Semantic proximity Read ↗

Prognostic implications of differences in telomere length between normal and malignant cells from patients with chronic myeloid leukemia measured by flow cytometrySemantic proximity Read ↗

Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.