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Article

A clinical and genetic study of SPG5A linked autosomal recessive hereditary spastic paraplegia.

Neurology - 22 Jul 2003

Wilkinson P A, Crosby A H, Turner C, Patel H, Wood N W, Schapira A H, Warner T T

Abstract excerpt

The authors performed a clinical and genetic study of a large consanguineous English family with uncomplicated autosomal recessive hereditary spastic paraplegia (ARHSP). Linkage to the previously described SPG5A locus was established with maximum multipoint lod score of 4.84. The locus was refined to a 23.6 cM interval between markers D8S1833 and D8S285. No evidence of oxidative phosphorylation defects was found...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12874406
DOI: 10.1212/01.wnl.0000069920.42968.8d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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