Article
Bimodal allele frequency distribution at Y-STR loci DYS392 and DYS438: no evidence for a deviation from the stepwise mutation model.
International journal of legal medicine - 1 Oct 2003
Gusmão Leonor, Krawczak Michael, Sánchez-Diz Paula, Alves Cíntia, Lopes Alexandra, Beleza Sandra, Carracedo Angel, Amorim António
Abstract excerpt
A deviation from the stepwise mutation model (SMM) has been suggested for the trinucleotide Y-STR locus DYS392, based upon its bimodal allele frequency distribution in various populations. The same type of distribution is also observed for the pentanucleotide Y-STR DYS438. In order to verify whether a departure from an SMM is likely for these two loci, we studied a large number of Portuguese male DNA samples...
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