Article
Radiation-induced genomic instability: radiation quality and dose response.
Health physics - 1 Jul 2003
Smith Leslie E, Nagar Shruti, Kim Grace J, Morgan William F
Abstract excerpt
Genomic instability is a term used to describe a phenomenon that results in the accumulation of multiple changes required to convert a stable genome of a normal cell to an unstable genome characteristic of a tumor. There has been considerable recent debate concerning the importance of genomic instability in human cancer and its temporal occurrence in the carcinogenic process. Radiation is capable of inducing...
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