Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary hemochromatosis: effect of excessive alcohol consumption on disease expression in patients homozygous for the C282Y mutation.

American journal of epidemiology - 15 Jul 2003

Scotet Virginie, Mérour Marie-Christine, Mercier Anne-Yvonne, Chanu Brigitte, Le Faou Thérèse, Raguénes Odile, Le Gac Gérald, Mura Catherine, Nousbaum Jean-Baptiste, Férec Claude

Abstract excerpt

Hereditary hemochromatosis is a common inherited disorder characterized by iron overload. A single mutation (C282Y) in the HFE gene is present in 80-95% of cases in populations of northern European extraction. The disorder presents a large phenotypic heterogeneity, and its expression can be influenced by environmental factors. This 1977-2002 study aimed to identify the influence of alcohol consumption on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine Transaminase
Share to Aspartate Aminotransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ferritins

Share to Hemochromatosis

Share to Iron Overload

Share to Pigmentation Disorders

Share to Statistics, Nonparametric

Share to Transferrin

Source

Identifiers

PMID: 12851225
DOI: 10.1093/aje/kwg123

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary hemochromatosis: effect of excessive alcohol consumption on disease expression in patients homozygous for the C282Y mutation.PMID 12851225Read ↗

Hereditary hemochromatosis: insights from the Hemochromatosis and Iron Overload Screening (HEIRS) Study.Semantic proximity Read ↗

Impact of HFE genetic testing on clinical presentation of hereditary hemochromatosis: new epidemiological data.Semantic proximity Read ↗

Genetic hemochromatosis update.Semantic proximity Read ↗

Revisiting hemochromatosis: genetic vs. phenotypic manifestationsSemantic proximity Read ↗

Genetic predisposition to iron overload: prevalence and phenotypic expression of hemochromatosis-associated HFE-C282Y gene mutation.Semantic proximity Read ↗

[Hereditary hemochromatosis: phenotypic study in a Spanish population].Semantic proximity Read ↗

Review article: haemochromatosis.Semantic proximity Read ↗

[Hemochromatosis International: therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr homozygous genotype].Semantic proximity Read ↗

Frequency and biochemical expression of C282Y/H63D hemochromatosis (HFE) gene mutations in the healthy adult population in Italy.Semantic proximity Read ↗

Heterozygosity for the hemochromatosis gene in liver diseases--prevalence and effects on liver histology.Semantic proximity Read ↗

[Hemochromatosis: the most common of rare diseases].Semantic proximity Read ↗

Epidemiology and diagnostic testing for hemochromatosis and iron overload.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.