Article
HLA-DRB1 gene polymorphism in patients with dilated cardiomyopathy.
Journal of Tongji Medical University = Tong ji yi ke da xue xue bao - 1 Jan 2000
Wang Q, Liao Y, Gong F, Mao H, Zhang J
Abstract excerpt
To probe into the genetic background and immunopathogenesis of dilated cardiomyopathy (DCM), HLA-DRB1 gene polymorphism in 68 patients with DCM and 175 normal control subjects were analyzed by using the polymerase chain reaction/sequence specific primer (PCR/SSP) techniques. It was found that the frequencies of HLA-DRB1* 15 and HLA-DRB1* 03 alleles were significantly lower in DCM patients than those in normal...
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