Article
A common 936 C/T gene polymorphism of vascular endothelial growth factor is associated with decreased breast cancer risk.
International journal of cancer - 10 Sept 2003
Krippl Peter, Langsenlehner Uwe, Renner Wilfried, Yazdani-Biuki Babak, Wolf Gerald, Wascher Thomas C, Paulweber Bernhard, Haas Josef, Samonigg Hellmut
Abstract excerpt
A common 936 C/T polymorphism in the gene for the vascular endothelial growth factor (VEGF) has been associated with VEGF plasma levels. In our case-control study, we investigated the role of this polymorphism for breast cancer risk. VEGF genotype was determined in 500 women with breast cancer and 500 sex- and age-matched healthy control subjects. Carriers of a 936T-allele were more frequent among controls...
Topics
- Adult
- Aged
- Aged, 80 and over
- Breast Neoplasms
- Case-Control Studies
- DNA Mutational Analysis
- DNA Primers
- DNA, Neoplasm
- Endothelial Growth Factors
- Female