Article
Long-term adiposity changes are related to a glucocorticoid receptor polymorphism in young females.
The Journal of clinical endocrinology and metabolism - 1 Jul 2003
Tremblay Angelo, Bouchard Luigi, Bouchard Claude, Després Jean-Pierre, Drapeau Vicky, Pérusse Louis
Abstract excerpt
Male and female preadolescents and adolescents who participated in phase 1 of the Québec Family Study, and who were retested about 12 yr later, were recruited and subdivided on the basis of a genetic variant within the intron 2 of the glucocorticoid receptor (GRL IVS2-BclI). The increase in sc adiposity over the 12-yr follow-up period in the 4.5/2.3 genotype female subgroup was more than twice that observed in...
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