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Article

The behavioral profile of severe mental retardation in a genetic mouse model of phenylketonuria.

Behavior genetics - 1 May 2003

Cabib Simona, Pascucci Tiziana, Ventura Rossella, Romano Valentino, Puglisi-Allegra Stefano

Abstract excerpt

Pah(enu2) mice, created by chemically induced genetic mutation, are characterized by biochemical phenotypes closely resembling untreated human phenylketonuria (PKU). However, studies conducted in adult Pah(enu2) mice have shown no indices of the severe mental retardation that characterizes untreated PKU. The present experiments explored recognition of novel spatial and non-spatial information in Pah(enu2) mice by...

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Identifiers

PMID: 12837019
DOI: 10.1023/a:1023498508987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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