Article
The behavioral profile of severe mental retardation in a genetic mouse model of phenylketonuria.
Behavior genetics - 1 May 2003
Cabib Simona, Pascucci Tiziana, Ventura Rossella, Romano Valentino, Puglisi-Allegra Stefano
Abstract excerpt
Pah(enu2) mice, created by chemically induced genetic mutation, are characterized by biochemical phenotypes closely resembling untreated human phenylketonuria (PKU). However, studies conducted in adult Pah(enu2) mice have shown no indices of the severe mental retardation that characterizes untrea...
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