Association of Leiden mutation in Factor V gene with hypertension in pregnancy and pre-eclampsia

Abstract excerpt

OBJECTIVE: To evaluate whether the V Leiden mutation is consistently associated with hypertension in pregnancy across populations of pregnant women. DESIGN: Meta-analysis of studies comparing women with and without hypertension in pregnancy for the V Leiden mutation. METHODS: Studies were identified with MEDLINE and EMBASE searches complemented with perusal of bibliographies of retrieved articles and...

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