Article
MHC polymorphism and disease resistance in Atlantic salmon (Salmo salar); facing pathogens with single expressed major histocompatibility class I and class II loci.
Immunogenetics - 1 Jul 2003
Grimholt Unni, Larsen Stig, Nordmo Rolf, Midtlyng Paul, Kjoeglum Sissel, Storset Arne, Saebø Solve, Stet René J M
Abstract excerpt
Few studies have yet addressed the functional aspects of MHC molecules in fish. To lay the foundation for this, we evaluated the association between disease resistance and MHC class I and class II polymorphism in Atlantic salmon. Standardized disease challenge trials were performed on a semi-wild Atlantic salmon population with subsequent MHC typing and statistical analysis. The pathogens employed were infectious...
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