Article
Characterization of polymorphic structure of SREBP-2 gene: role in atherosclerosis.
Atherosclerosis - 1 Jun 2003
Robinet Peggy, Védie Benoit, Chironi Gilles, Gariépy Jérôme, Simon Alain, Moatti Nicole, Paul Jean Louis
Abstract excerpt
Sterol regulatory element binding proteins (SREBPs) are membrane-bound transcription factors that control the metabolism of cholesterol and fatty acids in mammalian cells. We postulated that polymorphisms (SNPs) in SREBP-2 gene might influence lipid parameters and the risk of coronary atheroscler...
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