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Article

Effects of epistasis on phenotypic robustness in metabolic pathways.

Mathematical biosciences - 1 Jul 2003

Bagheri-Chaichian Homayoun, Hermisson Joachim, Vaisnys Juozas R, Wagner Günter P

Abstract excerpt

It is an open question whether phenomena such as phenotypic robustness to mutation evolve as adaptations or are simply an inherent property of genetic systems. As a case study, we examine this question with regard to dominance in metabolic physiology. Traditionally the conclusion that has been derived from Metabolic Control Analysis has been that dominance is an inevitable property of multi-enzyme systems and...

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PMID: 12788232
DOI: 10.1016/s0025-5564(03)00057-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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