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Article

Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees.

Molecular biology and evolution - 1 Aug 2003

Kitano Takashi, Schwarz Carsten, Nickel Birgit, Pääbo Svante

Abstract excerpt

We have investigated the pattern and extent of nucleotide diversity in 10 X-chromosomal genes where mutations are known to cause mental retardation in humans. For each gene, we sequenced the entire coding region from cDNA in humans, chimpanzees, and orangutans, as well as about 3 kb of genomic DNA in 20 humans sampled worldwide and in 10 chimpanzees representing two "subspecies." Overall nucleotide diversity in...

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PMID: 12777533
DOI: 10.1093/molbev/msg134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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