Article
Antiviral function of pyrrolidine dithiocarbamate against influenza virus: the inhibition of viral gene replication and transcription
12 Jun 2003
Abstract excerpt
The pathogenesis of influenza virus infection involves virus replication in epithelial cells of the respiratory tract and the degeneration of infected cells resulting from subsequent events.1 Influenza virus induces cellular degeneration following infection of cultured cells in vitro, and the cytopathic effect (CPE) occurs principally through apoptotic cell death.1–10 Influenza virus replication is an essential...
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