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Equatorial Segment Protein Defines a Discrete Acrosomal Subcompartment Persisting Throughout Acrosomal Biogenesis1

1 Sept 2003

Abstract excerpt

The equatorial segment of the acrosome underlies the domain of the sperm that fuses with the egg membrane during fertilization. Equatorial segment protein (ESP), a novel 349-amino acid concanavalin-A-binding protein encoded by a two-exon gene (SP-ESP) located on chromosome 15 at q22, has been localized to the equatorial segment of ejaculated human sperm. Light microscopic immunofluorescent observations revealed...

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PMID: 12773409
DOI: 10.1095/biolreprod.103.016675

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